Immunoassay
Immunoassay systems for every test location and any sensitivity.
We bring a unique mix of pragmatism and innovation to immunoassay system development. With experience and technologies covering every testing location and any immunoassay sensitivity, from lateral flow to single molecule detection, we will take the right approach to rapidly develop the right system for your intended diagnostic application.
Proven track record in innovative diagnostics
Leading diagnostic companies aspire to bring clinical, central-lab quality diagnostics to distributed labs, the point of care, and even home environments. But translating lab-quality immunoassays – like ELISA and advanced formats – into reliable, point-of-need solutions is a complex challenge.
With over 30 years working in diagnostics, we understand the importance of maintaining high diagnostic quality and precision outside traditional laboratory settings. While lateral flow technology remains a cornerstone, there’s growing demand for more sustainable options that also improve sensitivity and provide quantitative results.
Our approach merges pragmatic, interdisciplinary creativity with deep insight into the interaction of chemistry and biology within the final engineered product. With a proven track record in innovative diagnostics, our team covers every stage of development – from reagents to design for manufacture – backed by IP and proprietary know-how.
Partnering with TTP means working with an open, transparent, and engaged team of experts dedicated to supporting you at every step of the journey towards a high-quality, user-friendly diagnostic system that will set you apart.
The microFlex system accelerates time to market by enabling translation of existing immunoassay chemistries with minimal development. It mimics a central-lab workflow, automating vacuum tube-to-plasma processing with an integrated centrifuge, supports customisable workflows in a sealed cartridge to deliver central-lab quality assays, and has robust IP protection with a range of granted and pending patents on key technologies, including its centrifuge and vacuum-tube handling.
Ben Metcalf
Project Leader, TTP
The multi-disciplinary team at TTP are highly experienced and were able to rapidly assist us in the manufacturing of MosaiQ to build what is now an industry leading system. Their expertise, together with their drive to bring our idea to reality, made them the ideal partner.
Ed Farrell
Formerly President at Quotient
High sensitivity and high accuracy testing
High-sensitivity detection of proteins is enabling research and diagnostics in a range of areas. We are hopefully seeing the beginnings of a revolution in the treatment of neurological diseases, made possible by high-sensitivity protein detection as part of the drug discovery pathway. Once therapies reach the market, commercial tools for diagnosis, stratification and monitoring will be key. High-sensitivity detection technologies also allow new applications of less invasive matrices such as saliva and urine.
Similar technologies give increased accuracy and, in some cases, the ability to quantify proteins, RNA and small molecules. We see this as an opportunity to develop technologies that provide high levels of sensitivity while being sample type and target agnostic. Such multi-omic platforms will detect protein, small molecule and nucleic acid targets in a single test, translating into faster, more accurate and lower cost diagnostics for both existing and previously undiagnosable conditions.
Medical device software
Regulatory bodies worldwide want to ensure optimal outcomes when patients use the medical devices available in their region. Key contributors to this are patient safety, security of patient data, and patient satisfaction.
Patient safety entails the use of devices that pose no direct risk to patient wellbeing by any action or inaction, and no indirect risk by delivering potentially harmful misinformation. Patient security calls for the use of state-of-the-art security measures to prevent harm to the patient through cyber-security attacks. Patient satisfaction demands devices that offer the best possible care, typically through accuracy, time to results and ease of use.
To achieve these goals, regulatory bodies require that all medical device software is developed through regulated processes that address risk and quality at all stages. This creates significant and regionally varying requirements of documentation, verification, validation and testing throughout the development process. In turn, this increases development time and cost when compared with unregulated product development processes.
At TTP, we draw on our long-standing experience in diagnostics to reduce the impact of these requirements. We identify product and regulatory commonalities and invest in software component solutions that are pre-qualified for selected markets. Modules with well-categorized behaviours and capabilities have numerous advantages, informing the scope of early product investigation as well as reducing technical and schedule risk and development cost.
Discover how pre-qualified software solutions streamline medical device development while meeting regulatory demands. Read our expert insights here.
Innovation in lateral flow systems
In the last 5 years, the value of lateral flow tests has become apparent to almost everyone. They offer a rapid and simple means to delivering immunoassay results in clinical and distributed settings. Over time, these tests have demonstrated their robustness and evolved to improve sensitivity. Yet, there is ample scope to innovate. At TTP, we see multiple opportunities to improve quantification, cost, and the end user experience, be that through sample input or data output.
In particular, we are exploring new lateral flow reader systems to improve the sensitivity and quantification achievable with existing test strips. In products, these systems often need to meet demanding requirements in terms of space, cost and accessibility, which must be balanced with performance to deliver a device that can satisfy user needs. Our expertise in optics, thermal and fluidic control, as well in image analysis and data processing algorithms comes together in innovating lateral flow reader systems.
How we can help
Updating lab systems
Our multi-disciplinary Diagnostics team – with expertise in optics, electronics, software and liquid handling as well as in manufacturing, usability and complex system integration – can develop innovative solutions for existing lab-based immunoassay systems.
We can assist in sourcing and reviewing replacement parts or modules for end-of-life components, streamlining manufacturing and assembly processes to reduce costs, improving performance by upgrading optical, fluid-handling or thermal modules, and enhancing the user experiences through a human-centred design approach for consumable parts and interfaces.
Assay design and support
Our consultants include biologists and chemists with extensive experience in reagent development and QC, ELISAs, biochemistry molecular biology, cell biology and microbiology.
We can undertake de novo assay and reagent development, support the development, integration and verification of new or modified biochemical approaches or simply run your assay reagents on prototype systems we’ve designed during development and product testing.
Our expertise in critical areas such as bioconjugation, surface chemistry and protein biophysics helps to ensure the most important aspect of any immunoassay development, the biology, is put on the best path to success.
Lateral flow reader development
The addition of a digital read-out system to your lateral flow test can transform the utility of your assay. Our extensive experience in developing innovative, high-performance optical systems in the IVD sector enables us to deliver the sensitivity and precision needed to achieve lab-quality performance in lateral flow tests.
A major advantage of a digital readout for your lateral flow strip is the potential to send, collect and analyse data in the cloud. Our dedicated software team develops the necessary end-to-end solutions, covering everything from low-level communication protocols and hardware integration to user-accessible databases and reporting applications in your cloud environment.
Usability and CLIA waiving
As diagnostic testing moves closer to the patient, exceptional product usability is even more important. Our human factors engineering experts design intuitive, user-friendly instruments and consumables that meet end-user needs while complying with regulatory requirements.
We conduct comprehensive user risk assessments and task analyses, and both formative and summative usability studies to gain a deep understanding your workflows, pain points, and critical user interactions. This human-centred approach ensures your immunoassay diagnostic systems are accessible and safe to use, helping you achieve CLIA-waived status in the USA while supporting broad adoption and optimal patient outcomes globally.
Industrial design
Our industrial design team combines creativity with technical expertise to develop innovative product concepts that captivate users and enhance the overall user experience. With a deep understanding of clinical workflows and user needs, we create meaningful designs that blend ergonomics, aesthetics, and manufacturing feasibility. The result is diagnostic instruments and consumables that not only perform exceptionally but also inspire confidence among healthcare professionals and patients. Our holistic, user-centred approach to industrial design gives you an advantage in developing diagnostic systems that stand out in a crowded market.
Sample processing and pre-analytical workflows
We bring together expertise in biology, chemistry, material sciences, fluidic control and plastic moulding design to develop innovative solutions for processing complex sample types, including whole blood, CSF, saliva, faecal matter, urine, and more.
We design systems for dose control, sample filtration and centrifugation, bead- and chemical- based purification, haematocrit measurements, and other critical pre-analytical steps to help ensure your point-of-care diagnostics deliver results with the same quality and reliability as central-lab analysers. We balance technical sophistication, usability and cost-efficiency, to develop accessible, next-generation sample processing solutions for immunoassays.
Updating lab systems
Our multi-disciplinary Diagnostics team – with expertise in optics, electronics, software and liquid handling as well as in manufacturing, usability and complex system integration – can develop innovative solutions for existing lab-based immunoassay systems.
We can assist in sourcing and reviewing replacement parts or modules for end-of-life components, streamlining manufacturing and assembly processes to reduce costs, improving performance by upgrading optical, fluid-handling or thermal modules, and enhancing the user experiences through a human-centred design approach for consumable parts and interfaces.
Assay design and support
Our consultants include biologists and chemists with extensive experience in reagent development and QC, ELISAs, biochemistry molecular biology, cell biology and microbiology.
We can undertake de novo assay and reagent development, support the development, integration and verification of new or modified biochemical approaches or simply run your assay reagents on prototype systems we’ve designed during development and product testing.
Our expertise in critical areas such as bioconjugation, surface chemistry and protein biophysics helps to ensure the most important aspect of any immunoassay development, the biology, is put on the best path to success.
Lateral flow reader development
The addition of a digital read-out system to your lateral flow test can transform the utility of your assay. Our extensive experience in developing innovative, high-performance optical systems in the IVD sector enables us to deliver the sensitivity and precision needed to achieve lab-quality performance in lateral flow tests.
A major advantage of a digital readout for your lateral flow strip is the potential to send, collect and analyse data in the cloud. Our dedicated software team develops the necessary end-to-end solutions, covering everything from low-level communication protocols and hardware integration to user-accessible databases and reporting applications in your cloud environment.
Usability and CLIA waiving
As diagnostic testing moves closer to the patient, exceptional product usability is even more important. Our human factors engineering experts design intuitive, user-friendly instruments and consumables that meet end-user needs while complying with regulatory requirements.
We conduct comprehensive user risk assessments and task analyses, and both formative and summative usability studies to gain a deep understanding your workflows, pain points, and critical user interactions. This human-centred approach ensures your immunoassay diagnostic systems are accessible and safe to use, helping you achieve CLIA-waived status in the USA while supporting broad adoption and optimal patient outcomes globally.
Industrial design
Our industrial design team combines creativity with technical expertise to develop innovative product concepts that captivate users and enhance the overall user experience. With a deep understanding of clinical workflows and user needs, we create meaningful designs that blend ergonomics, aesthetics, and manufacturing feasibility. The result is diagnostic instruments and consumables that not only perform exceptionally but also inspire confidence among healthcare professionals and patients. Our holistic, user-centred approach to industrial design gives you an advantage in developing diagnostic systems that stand out in a crowded market.
Sample processing and pre-analytical workflows
We bring together expertise in biology, chemistry, material sciences, fluidic control and plastic moulding design to develop innovative solutions for processing complex sample types, including whole blood, CSF, saliva, faecal matter, urine, and more.
We design systems for dose control, sample filtration and centrifugation, bead- and chemical- based purification, haematocrit measurements, and other critical pre-analytical steps to help ensure your point-of-care diagnostics deliver results with the same quality and reliability as central-lab analysers. We balance technical sophistication, usability and cost-efficiency, to develop accessible, next-generation sample processing solutions for immunoassays.
Our approach and capabilities
We deliver across the entire life of a project, from opportunity discovery to production engineering. Discover how our interdisciplinary teams of experts collaborate to tackle the toughest product development challenges.
Our campus and facilities
Our award-winning campus has been designed with a clear vision. To create a space which can support our people and our clients as we develop and deliver the very best technology solutions.
Software capability at TTP
Engaged in all stages of software and product development, our software capability at TTP covers the full spectrum—from in-depth analysis and system architecture to prototype design, implementation, and test development.
Manufacturing capability at TTP
Working seamlessly with our development teams, we take clients' products through prototype builds, clinical trials, pilot manufacture and more. Using TTP Manufacturing reduces uncertainty, risk and time to market for our clients.
Meet some of the team
Giles Sanders
Dan Gare
Ben Metcalf
