Super resolution microscopy (SRM) takes the resolution of optical microscopy below the diffraction limit of light. This allows visualization of cellular details that could not previously be seen without using alternative techniques such as electron microscopy. Despite increased uptake in research areas including cell biology, neurobiology, microbiology, and drug discovery, the use of SRM has been limited by high ownership costs and a lack of well-established protocols and analysis methods. Now, with a variety of affordable, user-friendly SRM platforms entering the market, accompanied by a growing list of publications validating their utility, SRM looks set to become mainstream.

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